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Cure for Diabetes

A discovery that has shocked everyone, states that a number of scientists at a hospital in Toronto can prove that the body’s nervous system is known to help trigger diabetes. This discovery now opens the door to the possibility of a near cure of a terrible disease that millions of people are now suffering from.

It was discovered that mice suffering from diabetes were made healthy again almost overnight after scientists injected them with a substance that counteracted the effects of pain neurons that were not functioning properly in the pancreas.

While researchers are cautious and say that they still have to confirm any results in humans, they do expect to get results of human studies in about a year or so. It is also noted that any treatments that could result to help some patients is probably years away from being on the market.

This discovery of this cure for diabetes, has upset the conclusion that Type 1 diabetes was caused solely by the body’s immune system turning against itself. This type of diabetes is the most serious form of diabetes and usually starts during childhood.

Another discovery that was made is that Type 1 and Type 2 diabetes are much more similar than was previously thought. Also, it was concluded that the nerves play a role in some other inflammatory diseases.

It is now concluded that the diagnosis and treatment of many neuropathic diseases is ready to take a giant leap forward because of the research discovery.

For those suffering from Type 1, insulin replacement is the only treatment, but it does not prevent some of the side effects such as kidney failure or heart attack.

With Type 1, the pancreas doesn’t make enough insulin to get the glucose to the cells that need it. Type 2 diabetes produces insulin that is not used correctly. This is sometimes known as insulin resistance which results in glucose not being absorbed well.

The problems usually are from inflammation and then death of the cells that produce insulin in the pancreas.

It was earlier noted that there was a surprising similarity between diabetes and multiple sclerosis, which is a central nervous disease. The scientists became interested in the presence of a great number of nerves around the insulin producing cells which are pain neurons that are mainly used to let the brain know that tissue is damaged.

After suspecting that there was a link between nerves and diabetes, an old experimental trick was used. Capsaicin was injected to kill the sensory nerves in the pancreas of mice that had what was the equivalent of Type 1 diabetes. The biggest shock was that the blood cells of the mice began to produce insulin normally.

Since nerves secrete neuropeptides that control the function of islets in the cells, it was found that the mice with diabetes did not release enough of these neuropeptides causing a huge amount of stress on the islets. After injecting the mice with the capsaicin substance the results were amazing.

The inflammation in the cells cleared up and the diabetes disappeared. Some of the mice have stayed that way for over four months, just by having one injection.

It was discovered that the treatment curbed the insulin resistance of Type 2 diabetes. The major factor in Type 1 diabetes is the insulin resistance. Therefore it did suggest that the two illnesses are similar.

Research is now being done to confirm whether humans also have this connection between sensory nerves and diabetes. If there is a connection then further research will be done to determine if the treatment works on humans as well.

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