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Type 2 diabetes mellitus consists of an array of dysfunctions characterized by hyperglycemia and resulting from the combination of resistance to insulin action, inadequate insulin secretion, and excessive or inappropriate glucagon secretion. poorly controlled type 2 diabetes is associated with an array of microvascular, macrovascular, and neu…. A key recommendation of the recent diabetes feet australia (dfa) australian dfd strategy 2018-2022 was to ensure australia urgently developed new national dfd guidelines that reflected the most up-to-date robust evidence to guide standards of health care provision. with this project we aim to: adopt or adapt suitable international source dfd guideline recommendations to the multi-disciplinary. Nafld is often associated with type 2 diabetes, with nearly 50 million indian adults having both diseases. the findings of the research have been published in the journal diabetes..
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Our findings provide a foundation for preserving existing β-cell mass and for developing new therapeutic approaches that have the potential to successfully prevent thousands of type 2 diabetes. In the early 1990’s, clinicians’ choices for pharmacological management of type 2 diabetes were limited to insulin, sulfonylureas, and metformin. since then, multiple classes of agents have been discovered, approved, and put into clinical use. through a series of cardiovascular outcome trials and other clinical trials, some classes of agents have been found to have benefits on. The natural history of type 2 diabetes has been well described in multiple populations (1,,,,, –16) (rev. in (17,18).individuals destined to develop type 2 diabetes inherit a set of genes from their parents that make their tissues resistant to insulin (1,16,19,,,, –24).in liver, the insulin resistance is manifested by an overproduction of glucose during the basal state despite the presence.
