Sickle Cell Trait and The A1c Test : Information For Patients

Hemoglobin a1c the main fraction of glycated (glucose-bound) hemoglobin. since glucose remains bound to hemoglobin for the life of a red blood cell (~120 days), hemoglobin a1c values reflect blood glucose control over the past four months. hemolysis rupture of red blood cells. hemolytic anemia anemia resulting from hemolysis. hemorrhage. The a1c test can be used to diagnose type 2 diabetes and prediabetes. 1 the a1c test is also the primary test used for diabetes management. an a1c test is a blood test that reflects your average blood glucose levels over the past 3 months. the a1c test is sometimes called the hemoglobin a1c, hba1c, glycated hemoglobin, or glycohemoglobin test.. A1c reflects average glycemia over approximately 3 months. the performance of the test is generally excellent for ngsp-certified assays (www.ngsp.org).the test is the major tool for assessing glycemic control and has strong predictive value for diabetes complications (1–3).thus, a1c testing should be performed routinely in all patients with diabetes—at initial assessment and as part of.

The journal of pediatrics is an international peer-reviewed journal that advances pediatric research and serves as a practical guide for pediatricians who manage health and diagnose and treat disorders in infants, children, and adolescents.the journal publishes original work based on standards of excellence and expert review. the journal seeks to publish high quality original articles that are. In sickle cell anemia, one defective hemoglobin gene is inherited from each parent. if only one gene is inherited from one parent, then the condition is milder and referred to as sickle cell trait. symptoms of sickle cell anemia vary depending on its severity. patients with sickle cell trait may experience mild if any, symptoms at all.. A1c reflects average glycemia over approximately 3 months. the performance of the test is generally excellent for ngsp-certified assays (www.ngsp.org).the test is the major tool for assessing glycemic control and has strong predictive value for diabetes complications (1–3).thus, a1c testing should be performed routinely in all patients with diabetes—at initial assessment and as part of.

In sickle cell disease, a person inherits two genes for hemoglobin s, which causes the malformation, or sickling, of red blood cells, leading to anemia, repeated infections, and periodic episodes of pain. the a1c test is not used in diabetes patients with sickle cell anemia due to the shortened life span of red blood cells.. Hemoglobin a1c the main fraction of glycated (glucose-bound) hemoglobin. since glucose remains bound to hemoglobin for the life of a red blood cell (~120 days), hemoglobin a1c values reflect blood glucose control over the past four months. hemolysis rupture of red blood cells. hemolytic anemia anemia resulting from hemolysis. hemorrhage. Marked discrepancies between measured a1c and plasma glucose levels should prompt consideration that the a1c assay may not be reliable for that individual, since a relatively small percentage of patients have conditions such as sickle cell trait or hemoglobinopathies that skew a1c results..

The cause of scd is a defective gene, called a sickle cell gene. people with the disease are born with two sickle cell genes, one from each parent. if you are born with one sickle cell gene, it’s called sickle cell trait. people with sickle cell trait are generally healthy, but they can pass the defective gene on to their children.. The a1c test can be used to diagnose type 2 diabetes and prediabetes. 1 the a1c test is also the primary test used for diabetes management. an a1c test is a blood test that reflects your average blood glucose levels over the past 3 months. the a1c test is sometimes called the hemoglobin a1c, hba1c, glycated hemoglobin, or glycohemoglobin test.. The a1c test is used to monitor the glucose levels of patients who have been diagnosed with diabetes. in people who have hemoglobin variants such as hbs (sickle cell trait), some a1c tests give falsely high or low readings that can lead to the over-treatment or under-treatment of diabetes..